What Is Somatic Cell Nuclear Transfer. As we know it today nuclear transfer involves the transfer of the nucleus of a donor cell into an oocyte or early embryo from which the chromosomes have been removed. Somatic cell nuclear transfer scnt has a broad spectrum of potential applications including rescue of endangered species production of transgenic animals drug production and regenerative medicine.
When a nucleus is placed in oocyte cytoplasm the. Technology of somatic cell nuclear transfer. Unfortunately the efficiency of scnt is still disappointingly low.
Scnt is used to produce immunocompatible cells and tissues for xenotransplantation.
Nt escs negate ethical concerns with the use of human embryos to generate escs. Somatic cell nuclear transfer scnt cloning is an alternative means of developing cloned embryos nt embryonic stem cells nt escs and cloned transgenic animals. When a nucleus is placed in oocyte cytoplasm the. In genetics and developmental biology somatic cell nuclear transfer scnt is a laboratory strategy for creating a viable embryo from a body cell and an egg cell.