Phase Transfer Catalyst. Enable the use of inexpensive inorganic bases such as sodium hydroxide and other reagents and provide the ability to use less complex process equipmentis geared toward enabling successful implementation of a commercial phase transfer catalysis process. Ionic reactants are often soluble in an aqueous phase but insoluble in an organic phase unless the phase transfer catalyst is present.
Reaction is brought about by the use of small quantities of an agent which transfers one reactant across the interface into the other phase so that reaction can proceed. A phase transfer agent is added to transfer one of the reagents to a location where it can conveniently and rapidly react with another reagent. Catalyst structure may also be of.
Anomeric nucleophilic substitutions have been reported using mild ptc conditions for stereospecific entry to 1 thio β d mannosides and 1 thio β l rhamnosides.
Phase transfer catalysis is a sophisticated chemical technique which can be used to perform a variety of chemical reactions under mild conditions and with improved control. A phase transfer catalyst or ptc in chemistry is a catalyst which facilitates the migration of a reactant in a heterogeneous system from one phase into another phase where reaction can take place. A phase transfer agent is added to transfer one of the reagents to a location where it can conveniently and rapidly react with another reagent. The increasing application of phase transfer catalyst in the pharmaceutical sector has been driving the market growth.